Malignant Degeneration in Burn Scars

Malignant degeneration of scars in elderly people (Marjolin's ulcers).

TRPV3 Channel in Keratinocytes in Scars with Post-Burn Pruritus

Post-burn pruritus is a common and distressing sequela of burn scars. Empirical antipruritic treatments usually fail to have a satisfactory outcome because of their limited selectivity and possible side effects. Therefore, novel drug targets need to be identified. Here, we aimed to investigate the possible role of protease-activated receptor 2 (PAR2) and transient receptor potential vanniloid 3...

Psychometric properties of the Brisbane Burn Scar Impact Profile in adults with burn scars

OBJECTIVE The aim of the study was to determine the longitudinal validity, reproducibility, responsiveness and interpretability of the adult version of the Brisbane Burn Scar Impact Profile, a patient-report measure of health-related quality of life. METHODS A prospective longitudinal cohort study of patients with or at risk of burn scarring was conducted at three assessment points (at baseli...

Pressure garment therapy (PGT) of burn scars: evidence-based efficacy.

Hypertrophic burn scars pose a challenge for burn survivors and providers. In many cases, they can severely limit a burn survivor's level of function, including work and recreational activities. A widespread modality of prevention and treatment of hypertrophic scarring is the utilization of pressure garment therapy (PGT). Despite the magnitude of the problem of hypertrophic scarring and the ubi...

Bilayer dermal matrix for the treatment of painful burn scars.

UNLABELLED  Background. Outcomes following burn injury have improved considerably in recent years due to early excision and skin grafting. Despite a reduction in late burn complications, up to 70% of patients experience long-term pain at both the injured area and the skin-grafted scar. Current therapies do not ameliorate these symptoms for a majority of these patients. This report present...